Bpharm 5th-Semester Notes in pdf – Free Download
Bpharm 5th-Semester Notes Subject:
Medicinal Chemistry 2
Industrial Pharmacy 1
Pharmacology 2
Pharmacognosy and Phytochemistry 2
Pharmaceutical Jurisprudence
Bpharm 5th Semester Notes Download
MEDICINAL CHEMISTRY – II
This subject is designed to impart fundamental knowledge on the structure, chemistry and therapeutic value of drugs. The subject emphasizes on structure activity
relationships of drugs, importance of physicochemical properties and metabolism of
drugs. The syllabus also emphasizes on chemical synthesis of important drugs under each class.
Unit 1
Antihistaminic agents, H1–antagonists, H2-antagonists, Gastric Proton pump inhibitors, Anti-neoplastic agents, Alkylating agents, Antimetabolites, Antibiotics, Plant products, Miscellaneous
Unit 2
Anti-anginal, Vasodilators, Calcium channel blockers, Diuretics, Anti-hypertensive Agents
Unit 3
Anti-arrhythmic Drugs, Anti-hyperlipidemic agents, Coagulants and Anticoagulants, Drugs used in Congestive Heart Failure
Unit 4
Drugs acting on Endocrine, Sex hormones, Drugs for erectile dysfunction, Oral contraceptives, Thyroid and antithyroid, Corticosteroids
Unit 5
Antidiabetic agents, Local Anesthetics, Benzoic Acid derivatives, Amino Benzoic acid derivatives, Lidocaine/Anilide derivatives, Miscellaneous
INDUSTRIAL PHARMACY-I
Course enables the student to understand and appreciate the influence of
pharmaceutical additives and various pharmaceutical dosage forms on the performance of the drug.
Unit 1
Preformulation Studies (Full)
Unit 2
Tablets , Liquid Orals
Tablets
Definition: Tablets are solid dosage forms containing medicinal substances with or without suitable excipients. They are intended for oral administration.
Liquid Orals
Definition: Liquid orals are liquid dosage forms containing medicinal substances dissolved or suspended in a suitable liquid medium for oral administration.
Unit 3
Capsules (Hard gelatin & Soft gelatin), Pellets
Capsules
Capsules are solid dosage forms in which the drug is enclosed within either a hard or soft soluble shell. The shell is typically made of gelatin, although alternatives like hydroxypropyl methylcellulose (HPMC) are available for vegetarian or vegan formulations.
Soft Gelatin Capsules
Definition: Soft gelatin capsules are one-piece capsules used for liquid or semi-solid drug formulations. They are made of a more flexible gelatin that can encapsulate oils and active ingredients in solution or suspension.
Pellets
Definition: Pellets are small, free-flowing, spherical or semi-spherical solid particles used in drug formulations. They can be used in various dosage forms, including capsules, tablets, and suspensions.
Unit 4
Parenteral Products, Ophthalmic Preparations
Parenteral Products
Definition: Parenteral products are sterile drug formulations administered by injection through one or more layers of skin or mucous membranes.
Ophthalmic Preparations
Definition: Ophthalmic preparations are sterile products specifically designed for application to the eye.
Unit 5
Cosmetics, Pharmaceutical Aerosols, Packaging Materials Science
PHARMACOLOGY-II
This subject is intended to impart the fundamental knowledge on various aspects
(classification, mechanism of action, therapeutic effects, clinical uses, side effects and
contraindications) of drugs acting on different systems of body and in addition, emphasis on the basic concepts of bioassay.
Unit 1
Pharmacology of drugs acting on cardio vascular system
(Introduction to hemodynamic and electrophysiology of heart, Drugs used in congestive heart failure, Anti-hypertensive drugs, Anti-anginal drugs, Anti-arrhythmic drugs, Anti-hyperlipidemic drugs).
Unit 2
Pharmacology of drugs acting on cardio vascular system
(Drugs used in the therapy of shock, Hematinics, coagulants and anticoagulants, Fibrinolytics and anti-platelet drugs, Plasma volume expanders).
Pharmacology of drugs acting on urinary system ( Diuretucs and Anti-diuretics)
Unit 3
Autocoids and related drugs
(Introduction to autacoids and classification, Histamine, 5-HT and their antagonists, Prostaglandins, Thromboxanes and Leukotrienes, Angiotensin, Bradykinin and Substance P, Non-steroidal anti-inflammatory agents, Anti-gout drugs, Antirheumatic drugs).
Unit 4
Pharmacology of drugs acting on endocrine system
( Basic concepts in endocrine pharmacology. Anterior Pituitary hormones- analogues and their inhibitors, Thyroid hormones- analogues and their inhibitors, Hormones regulating plasma calcium level- Parathormone, Calcitonin and
Vitamin-D, Insulin, Oral Hypoglycemic agents and glucagon, ACTH and corticosteroids).
Unit 5
Pharmacology of drugs acting on endocrine system
( Androgens and Anabolic steroids, Estrogens, progesterone and oral contraceptives, Drugs acting on the uterus)
PHARMACOGNOSY AND PHYTOCHEMISTRY II
The main purpose of subject is to impart the students the knowledge of how the
secondary metabolites are produced in the crude drugs, how to isolate and identify and produce them industrially. Also this subject involves the study of producing the plants and phytochemicals through plant tissue culture, drug interactions and basic principles of traditional system of medicine.
Unit 1
Metabolic pathways in higher plants and their determination
Unit 2
Alkaloids, Phenylpropanoids and flavonoids, Steroidal cardiac & triterpenoids glycoside, Glycosides, Volatile oil, Iridoids, other terpernoids and Napthaquinones
Unit 3
Terpenoids, Glycosides, Alkaloids, Resins
Unit 4
Forskolin, Sennoside, Artemisinin, Diosgenin, Digoxin, Atropine, Podophyllotoxin, Caffeine, Taxol, Vincristine and Vinblastine
Unit 5
Basics of Phytochemistry
Phytochemistry is the study of the chemicals derived from plants. These chemicals, known as phytochemicals, play important roles in plant growth, defense, and interaction with their environment. Here are the basics of phytochemistry:
PHARMACEUTICAL JURISPRUDENCE
This course is designed to impart basic knowledge on important legislations related to the profession of pharmacy.
Unit 1
Drugs and Cosmetics Act, 1940 and its rules 1945
Unit 2
Drugs and Cosmetics Act, 1940 and its rules 1945
Unit 3
Pharmacy Act –1948, Medicinal and Toilet Preparation Act –1955, Narcotic Drugs and Psychotropic substances Act-1985 and Rules
Unit 4
Study of Salient Features of Drugs and Magic Remedies Act and its
rules, Prevention of Cruelty to animals Act-1960, National Pharmaceutical Pricing Authority
Unit 5
Pharmaceutical Legislations, Code of Pharmaceutical ethics, Medical Termination of Pregnancy Act, Right to Information Act, Introduction to Intellectual Property Rights (IPR)
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